Therapeutics Royalty Investments
Therapeutics royalty investments have become a distinct asset class in life sciences, providing access to biopharma innovation through diversified royalty streams. This chapter introduces a quantamental approach to valuing companies and assets in this sector.
Daraxonrasib: Independent Valuation of Royalty Pharma’s Royalty Deal
This paper presents a detailed valuation of the daraxonrasib royalty deal between Royalty Pharma and Revolution Medicines.
Using epidemiology-driven peak-sales modeling and a probabilistic scenario engine, it assesses commercial outcomes and royalty economics.
Results include rNPV, IRR, scenario distributions, and sensitivity to major value drivers.
Quarterly Update – Q3 2025: Royalty Pharma (RPRX)
This new update applies the Quantamental Valuation and Risk Framework to Royalty Pharma’s latest quarterly disclosures (November 2025). It highlights revisions to portfolio assumptions, valuation impacts, and key clinical catalysts expected through 2026.
Explore my first white paper focused on the therapeutics royalty investment business.
While these companies are typically valued like traditional pharma or biotech firms, this study offers a new valuation and risk assessment perspective that better captures their distinct business model and value drivers.
Using Royalty Pharma (RPRX) as an example, the study illustrates how an investment vehicle approach can better capture portfolio performance and the drivers of long-term value creation.
It also lays the groundwork for future research, applying a data driven quantamental framework to establish consistent valuation standards for this asset class.
This research is provided for informational and educational purposes only. It is intended to present a conceptual and analytical framework for understanding the valuation and risk analysis of royalty-based investment structures. The material contained herein does not constitute, and should not be construed as, an offer, solicitation, or recommendation to buy or sell any security, financial instrument, or investment product.
Nothing in this paper should be relied upon for the purpose of making investment decisions or carrying out any transaction. The author and Lend-Rx SAS make no representations or warranties as to the accuracy, completeness, or timeliness of the information contained herein and accept no liability for any loss or damage arising from its use.